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#204150 - 01/07/12 02:58 AM Re: Leukemia/Lymphoma? [Re: Woodreb]
kelso Offline
Veteran

Registered: 02/15/10
Posts: 1490
Loc: Kansas
Likes: 38
thank you guys

This sucks, really bad.

Lisa- I hear you and am listening although you probably want to slap me silly! He has been treated with 60 days of doxy at 400 mg a day..the aggressive dose would be (5mg/lb) about 700 mg a day for? He has now been on clindamycin for 3 weeks as well.

I keep everything you say in mind, everytime I think it might be that we just need this increased doxy and then something else pops up...life threatening skin infections, positive cancer testing ect and I talk with 3 different vets and all the recs ect. Vasculitis/necrotizing fasc/itp/imha/cancer/infection/ and so on, I can talk with them again about the doxy for the 4th time, I will do that, as you have said it could be life or death.

The one thing I do know 100% is that Kelso is the stongest dog I have ever met. He tries everyday to be better, it is hard to explain but you can see it all over his face although everyone knows something is going on inside of him. His quality of life right now is most affected by his muscle wasting. He can no longer run after a ball and cannot get into the car on his own, his two favorite things to do (chase the ball and go on car rides). My mom played ball with him inside on New Year's Eve and he loved that, he loves her so much and the feeling is mutual smile After two laps up and down the street he is done, but he does enjoy the fresh air and walks. Otherwise his mentation is very clear and he acts very much like himself except that he is frustrated at times that he can't chase his ball ect. His weight is stable.

And on a lighter note, a pic from a good day, Jan2nd. We had great holidays! I hate having my pic taken but when my husband figures out how to use the camera it is nice to get some pics with the dogs

Me and my boy wub Love him so much and will not and cannot come to terms right now that he will not get better. Trying to stay positive

_________________________
-Steph

GSD's
Allie, gotcha 7/2007
Riko z Vom Weberhaus, "Fez" 7/29/2012

forever our angels
Meeka, b. 10/31/1994-11/26/2006
Kelso, b. 9/3/2006-2/9/2012


Top Likes: 0 
#204154 - 01/07/12 04:23 AM Re: Leukemia/Lymphoma? [Re: kelso]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19440
Loc: Northern CA
Likes: 255
Here is what I believe.

I believe that blood infections can lead to blood and lymph cancers. I believe this can be one reason for a higher incidence of hemangiosarcoma and lymphosarcoma in GSDs, because they are more susceptible to infections. There are a ton more infections out there than tick diseases, and there are a ton of tick diseases that I'm sure we haven't discovered yet. (I have been accused on the tick list of looking in dark places for things that may or may not be there, but when it comes to saving a life, I go where the logic and probabilities take me!)

I have read the studies that show that doxy has a wide range of surprising actions, from infection, to cancer to autoimmune and/or inflammatory disease. It covers so many different bases.

It's very possible that those dogs on the tick list had lymphoma. It's also very possible that it was caused by a tick disease or some other doxy-susceptible bug, and the doxy helped treat both the underlying infection and the cancer. Or that treating the underlying infection allows the body to fight the cancer, I dunno.

Vets have a saying. No dog should die without the benefits of steroids. I say, no dog should die without the benefits of doxy, particularly in situations where there are many very good reasons for trying it. At some point though, it's too late, and waiting for these vets and specialists to dink around, saddens and frustrates me. Life is precious, and it's very very fragile.

Kelso was on the conservative dose, the aggressive dose would be double that. (Before I had a permanent script for Max, I used the Bird Biotic from here: http://www.lambertvetsupply.com/Bird_Bio...ion-P39052.aspx but amazon and all sorts of places have it.

My heart breaks for you guys.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800954/

http://www.ncbi.nlm.nih.gov/m/pubmed/17337646/

http://www.ncbi.nlm.nih.gov/m/pubmed/3180079/

http://www.ncbi.nlm.nih.gov/m/pubmed/3874329/

http://www.bonecancerdogs.org/main/document/111 (Lymphoma just mentioned here)


It has shown some promise in certain types of eye lymphomas, currently being studied:

http://www.sciencedaily.com/releases/2006/10/061003191625.htm

http://www.ncbi.nlm.nih.gov/m/pubmed/19373893/

http://www.lymphomation.org/type-malt.htm

http://www.lymphomation.org/type-extranodal.htm (see #5, or search for doxycycline)

http://de-de.facebook.com/note.php?note_id=174680658363&comments&ref=mf (this study didn't show what they were looking for, but without looking at the studey (conducted by UC Davis), hard to comment on it

_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

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#204155 - 01/07/12 05:35 AM Re: Leukemia/Lymphoma? [Re: kelso]
arycrest Offline
Pooh-Bah

Registered: 02/11/10
Posts: 2488
Loc: Central Florida
Likes: 86


hugging hugging hugging hugging Steph & Kelso hugging hugging hugging hugging
I'm so sorry, wish I could say or do something to help, but know you and Dan are doing everything humanly possible for your boy! Keeping you and Kelso in my prayers!


Edited by arycrest (01/07/12 05:36 AM)
_________________________
Gayle
Faith, Ledgie & Scooby
My Bridge Kids: Andy, Abbey, Tasha, Tex, Echo, Yukon, JR, Too, Niki, Bo, Ringer, Kelly, Honey, Mac, Slider & Bruiser

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#204159 - 01/07/12 07:57 AM Re: Leukemia/Lymphoma? [Re: kelso]
Qyn Offline
Pooh-Bah

Registered: 02/20/10
Posts: 1964
Loc: Victoria, Australia
Likes: 47
That is a great photo Steph, Kelso looks mighty fine for dog who is not 100% - hurry up Dan and figure out the damn camera ... ya know we love photos!

I've got my fist down the fat ladies throat so no singing is expected in the near future so that base is covered.

hugging Best wishes beaming your way from downunder. Here's one for Kelso for when he is ready. fetch
_________________________
Alison
~~~~~~~~~~
Nix (derivative of Phoenix) Black GSD born 6 June 2011 (Gotcha day 9 Dec 2013)

Quynne gsdhalo - Black Female GSD - Sept 29, 2004 - 11 Nov 2013 Deeply missed

If you don't agree with me ... you are just not listening well enough. smile

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#204175 - 01/07/12 10:20 AM Re: Leukemia/Lymphoma? [Re: Qyn]
kaisersmom Offline
Old Hand

Registered: 02/14/10
Posts: 805
Loc: Northwest OH
Likes: 61
No words of wisdom from me - just hoping for the best for Kelso. I went back to the beginning and re-read a lot of this thread. It is just so darn sickening to think this all may have resulted from his booster vaccines. Not blaming anyone - but just sickening.

Here's hoping for many good days ahead for Kelso and his family! hugging And you both look great in the photo!!

_________________________
Pat

Marshall Dillon or Dillon - 16 months old
Kaiser - 11 1/2 yrs old - At the Bridge
Ray (Radar) - 8 yrs old - At the Bridge

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#204186 - 01/07/12 12:02 PM Re: Leukemia/Lymphoma? [Re: kaisersmom]
RileyAnna Offline
Addict

Registered: 04/12/10
Posts: 536
Likes: 8
Oh Steph, I wish there was something I could say to make it better. I really know how you feel as I am dealing with a very similar situation. Beautiful photo of the two of you together. Take lots of photos. I even took a video of Riley the other day of just his eyes blinking. I just love it. You and Kelso are in my prayers.

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#204191 - 01/07/12 12:37 PM Re: Leukemia/Lymphoma? [Re: RileyAnna]
Wisc.Tiger_Val Offline
Member First - Owner Second "The Watcher"

Registered: 01/18/10
Posts: 8699
Loc: Wisconsin
Likes: 261
Steph, sending you my best wishes for you and your boy Kelso.
_________________________
Val da Tiger

Fuzzybutt the cat.
Neilla the Big White puppy.

RIP Cheyenne - AKA: Digger, CheyChey Girl, Cheyenne Large and In charge. 2/16/02 - 2/27/16
RIP DeeDee - AKA: DD Poo, Little Bit, Binky (part of the Binky and Booboo team) 6/23/02-6/20/11
RIP Lakota - AKA: Bubba, Big Boy, BooBoo (the other part of the Binky and BooBoo team). 1/19/03-9/19/2011
RIP Raya - AKA: Raz-a, Ray a Sunshine, RayBestos, the little one, Silly Girl. 9/21/05 - 6/27/14

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#204267 - 01/07/12 09:07 PM Re: Leukemia/Lymphoma? [Re: Wisc.Tiger_Val]
Mary Jane Offline
Carpal Tunnel

Registered: 02/16/10
Posts: 2682
Likes: 123
Lisa is right, of course, about the origins of malignancies in the immune system. I mean GALT lymphoma is treated with antibiotics for the bacteria in the gut that induce the immune response that make way for the cancer....."that live in the house that Jack built".

Whatever is impairing Kelso's health-he is fighting hard and you are fighting. Put differently-you are doing everything you can and your big gorgeous boy is not anxious to leave you.

Please take some comfort in that.

Many best wishes to you both,
Mary Jane

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#204286 - 01/08/12 12:17 AM Re: Leukemia/Lymphoma? [Re: Mary Jane]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19440
Loc: Northern CA
Likes: 255
Originally Posted By: Mary Jane
Whatever is impairing Kelso's health-he is fighting hard and you are fighting. ...


hugging


More about pred use in lymphosarcoma:

Prednisone and prednisolone are central players in cancer chemotherapy protocols, most commonly for lymphosarcoma. And the good news is that they really make a difference in both life quality and life span. Oncologists are achieving median survival times of 10-14 months using these chemo protocols. This is most definitely worth considering.
http://www.dogcancerblog.com/prednisone-for-dog-cancer-2/
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#204295 - 01/08/12 04:30 AM Re: Leukemia/Lymphoma? [Re: MaxaLisa]
bianca Offline
Carpal Tunnel

Registered: 05/14/10
Posts: 8875
Loc: Queensland. Australia
Likes: 149
Hoping today was a good day for you both, that is a lovely photo wub hugging
_________________________
Molly Moo (aka The Piranha, 4 legged mouth) GSD (31/10/09)
Cooper GSD (The Gremlin) 19/10/11
Texas - Tabby cat (Feb 1996-2013) Run free sweet Teppie
Paris - Tabby cat (Feb 1996-2013) Run free my beautiful girl.

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