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#315807 - 05/20/14 11:19 PM Tick disease update
MaxaLisa Offline

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Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
I think I'll just make a running thread of TBD news that is worth sharing, for anyone to post in. Here is the link to our TBD sticky in the Health Index: http://germanshepherdhome.net/forum/ubbthreads.php/topics/1594/Ticks_and_Tick_Diseases#Post1594

I'll start by posting something about lyme in the South. It's long been said that there is no lyme in the south. However, then they found that there is STARI, which doesn't show up on regular lyme tests, and behaves similar to lyme. Now they found two new species in the south:

Quote:
...Dr. Kerry Clark, associate professor of public health at the University of North Florida in Jacksonville, and his colleagues have found additional cases of Lyme disease in patients from several states in the southeastern U.S. These cases include two additional Lyme disease Borrelia species recently identified in patients in Florida and Georgia.

Overall, 42 percent of 215 patients from southern states tested positive for some Lyme Borrelia species. More than 90 cases of Lyme infection were confirmed among patients from Florida, Georgia, North Carolina, Texas and Virginia. Of these southern cases, 69 percent were found to have infection with B. burgdorferi, 22 percent with B. americana and 3 percent with B. andersonii. ...

http://www.infectioncontroltoday.com/new...n-patients.aspx

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#316380 - 05/28/14 10:30 PM Re: Tick disease update [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
New TBD in Europe:

Neoehrlichia mikurensis
http://sahlgrenska.gu.se/english/news_an...sons.cid1216980
http://cid.oxfordjournals.org/content/early/2014/04/21/cid.ciu189.abstract

"The most frequent symptoms were fever (11/11), localized pain afflicting muscles and/or joints (8/11), vascular and thromboembolic events (6/11), that is, deep vein thrombosis (4), transitory ischemic attacks (2), pulmonary embolism (1), and arterial aneurysm (1). Typical laboratory findings were elevated C-reactive protein, leukocytosis with neutrophilia, and anemia. "
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#317831 - 06/16/14 11:20 AM Re: Tick disease update: ohio [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Expect to see more Lyme, etc., in Ohio, with the increased tick population.

Quote:
Emergence of Ixodes scapularis and Borrelia
burgdorferi, the Lyme disease vector and agent, in Ohio.
Wang P, Glowacki MN, Hoet AE, Needham GR, Smith KA, Gary
RE, Li X. Frontiers in Cellular Infection Microbiology,
2014 Jun 4;4:70.

http://doi.org/10.3389/fcimb.2014.00070
<http://doi.org/10.3389/fcimb.2014.00070>

Abstract

Lyme disease, the most common vector-borne disease in the United
States, is caused by a tick-borne infection with Borrelia
burgdorferi. Currently, Ohio is considered by the Centers
for Disease Control and Prevention (CDC) to be non-endemic for
Lyme disease. The low incidence of Lyme disease in this state was
largely attributed to the absence of the transmitting vector,
Ixodes scapularis, commonly known as the blacklegged
tick. However, a tick surveillance program established by
Ohio Department of Health indicated that the number of I.
scapularis in Ohio had increased sharply in recent years,
from 0 - 5 ticks per year during 1983-2008 to 15 in 2009,
40 in 2010, and 184 in 2011.

During the fall deer hunting season, examination of deer heads
submitted to Ohio Department of Agriculture found 29 I.
scapularis from 7 counties in 2010 and 1,830 from 25
counties in 2011. As of 2012, the tick had been found in 57 of
the 88 counties of Ohio. In addition, all three active
stages (larva, nymph, and adult) of I. scapularis were
found in Tiverton Township of Coshocton County,
demonstrating the presence of established tick populations
at this central Ohio location. Of 530 nymphal or adult I.
scapularis analyzed by quantitative polymerase chain
reaction (qPCR), 32 (6.1%) tested positive for the B.
burgdorferi flaB gene, ranging from 36 to 390,000 copies
per tick. Antibodies to B. burgdorferi antigens were
detected in 2 of 10 (20%) field-captured Peromyscus
leucopus from Tiverton Township, and in 41 of 355 (11.5%)
dogs residing in Ohio.

Collectively, these data suggest that the enzootic life cycle of
B. burgdorferi has become established in Ohio, which
poses risk of Lyme disease to people and animals in the
area.

http://doi.org/10.3389/fcimb.2014.00070
<http://doi.org/10.3389/fcimb.2014.00070>

Free, full text:
http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00070/full
<http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00070/full>
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#318842 - 06/28/14 04:37 PM Re: Tick disease update: cataracts [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Quote:
Bacterial tick-borne diseases caused by Bartonella
spp., Borrelia burgdorferi sensu lato, Coxiella
burnetii, and Rickettsia spp. among patients with
cataract surgery. Chmielewski T, Brydak-Godowska
J, Fiecek B, Rorot U, S&#281;drowicz E, Werenowska M,
Kopacz D, Hevelke A, Michniewicz M, K&#281;cik D,
Tylewska-Wierzbanowska S. Medical Science Monitor. 2014 Jun
5;20:927-31.

http://doi.org/10.12659/MSM.890149
<http://doi.org/10.12659/MSM.890149>

Abstract

Background
Clinical data have shown that tick-borne diseases caused by
Borrelia burgdorferi sensu lato, Bartonella spp.,
Coxiella burnetii, and Rickettsia spp. can affect the
central nervous system, including the eye. The aim of this
study was to establish a relationship between the incidence of
cataract and evidence of bacterial infections transmitted by
ticks.

Material/Methods
Fluid with lenticular masses from inside of the eye and blood
from 109 patients were tested by PCR and sequencing. Sera from
patients and the control group were subjected to serological
tests to search specific antibodies to the bacteria.

Results
Microbiological analysis revealed the presence of Bartonella
sp. DNA in intraoperative specimens from the eye in 1.8% of
patients. Serological studies have shown that infections
caused by B. burgdorferi sensu lato and Bartonella sp.
were detected in 34.8% and 4.6% of patients with cataract
surgery, respectively.


Conclusions
Presence of DNA of yet uncultured and undescribed species of
Bartonella in eye liquid indicates past infection with
this pathogen. Specific antibodies to B. burgdorferi
sensu lato and Bartonella sp. are detected more
frequently in patients with cataract compared to the
control group. This could indicate a possible role of
these organisms in the pathological processes within
the eyeball, leading to changes in the lens. Further studies
are needed to identify Bartonella species, as well as
to recognize the infectious mechanisms involved in cataract
development.
http://doi.org/10.12659/MSM.890149
<http://doi.org/10.12659/MSM.890149>

Free, full text pdf file:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049946/pdf/medscimonit-20-927.pdf
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#320879 - 07/31/14 10:12 AM Re: Tick disease update [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Blog post about how poorly PCR does in testing for lyme, which can be generalized to other tbd testing. Many of the panels run by the major labs use PCR tests.

Also talks about the emergence of other "lyme" diseases (which don't show up on the standard canine lyme tests) and the problem of babesia, which typically is not tested for.

http://lymemd.blogspot.com/2014/07/the-lyme-world-on-its-head-rapidly.html
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#321670 - 08/16/14 12:43 PM Re: Tick disease update [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
A story about a woman in Australia, and her family, that has Lyme. Significant primarily because many say there is no Lyme in Australia:
http://m.dailytelegraph.com.au/newslocal...4adf642e1fab1f2
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#321678 - 08/16/14 02:28 PM Re: Tick disease update [Re: MaxaLisa]
PaddyD Offline
Old Hand

Registered: 10/05/12
Posts: 833
Loc: Massachusetts
Likes: 85
Anaplasmosis (deer tick disease) has knocked Abby for a loop. 2 cyles (March and June) of
doxycyclin have either contributed to her malaise or failed to cure it. She has lost 11 pounds
and is lame and weak. After extensive (expensive) and redundant tests by multiple vets,
including xrays, she should be in good health. Got 4 different vets scratching their heads
(hopefully from a tick bite). I did get one miracle pill: Mirtazapine, which gave her some
of her appetite and attitude back, also reduced some of the lameness.
Lesson learned: stick with one vet. At least around here, they all seem to be equally
knowledgeable/ignorant. Her blood was tested 3 times: good; good; good. Tick panel
in June (and medication) was done too early following the March cycle and second vet
should have known that because dog will continue to test postive for 'a while' (forever?)
after treatment.
Side benefit: learned that her hips, elbows and spine are in very good shape.
Going in tomorrow for fasting blood test to check pancreas a nutrient
absorption.
Admin please move this if it is in the wrong thread, thank you.
_________________________
Pat
=====================
Abby - GSD - 7/4/2009
=====================



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#321680 - 08/16/14 03:01 PM Re: Tick disease update [Re: PaddyD]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Yes, they will be able to test positive for awhile, but symptoms *should* resolved with treatment. The type of test used can be meaningful, and the "trend" of the movement of the titers is important too. There *may be* coinfections, which complicate treatment. Sometimes just bumping up to the aggressive dose of doxy (10mg/kg BID), which is twice as high as conventional treatment (and the tick list recommends 6-8 weeks depending on symptoms). Undertreated is often recurrent, but sometimes, I think, there is more going on that may be hard to get at. For E. canis, sometimes a different drug is used ( http://www.vetinfo.com/treating-canine-ehrlichiosis-with-imidocarb-imizol.html ), but I do not know how effective it is for E. equine (now anaplasmosis). Monitoring the regular bloodwork on a regular basis seems like an important thing to do to help determine when retreatment is necessary.

You're right about that "one vet", unless you find one that knows an astounding amount in the TBD area. Most don't, and as long as you have a vet that is willing to work with you and open to info, that seems to be the most helpful. I guess all those gobs of tests bring some sense of security of knowing what it's not (and a lighter wallet), but it sure is frustrating when there when you see your dog not well frown


Edited by MaxaLisa (08/16/14 03:02 PM)
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#321799 - 08/19/14 12:48 PM Re: Tick disease update [Re: MaxaLisa]
PaddyD Offline
Old Hand

Registered: 10/05/12
Posts: 833
Loc: Massachusetts
Likes: 85
Originally Posted By: MaxaLisa

You're right about that "one vet", unless you find one that knows an astounding amount in the TBD area. Most don't, and as long as you have a vet that is willing to work with you and open to info, that seems to be the most helpful. I guess all those gobs of tests bring some sense of security of knowing what it's not (and a lighter wallet), but it sure is frustrating when there when you see your dog not well frown

After 3 days on Mirtazapine and prednisone, Abby has bounced back significantly. Still
has a way to go but is returning to her old (young) self. Hoping to see the weight come back very soon.
_________________________
Pat
=====================
Abby - GSD - 7/4/2009
=====================



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#321832 - 08/20/14 06:11 AM Re: Tick disease update [Re: PaddyD]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Steroid use in a TBD can be pretty dicey, the line between infection and inflammation. Can be very hard to balance. I'm really glad that she is feeling better though!
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#321835 - 08/20/14 07:10 AM Re: Tick disease update [Re: MaxaLisa]
PaddyD Offline
Old Hand

Registered: 10/05/12
Posts: 833
Loc: Massachusetts
Likes: 85
Originally Posted By: MaxaLisa
Steroid use in a TBD can be pretty dicey, the line between infection and inflammation. Can be very hard to balance. I'm really glad that she is feeling better though!

She's on 5mg/day. I will change it to every other day soon. Then phase it out.
So good to have my dog back!
Thanks for being there. thanks
_________________________
Pat
=====================
Abby - GSD - 7/4/2009
=====================



Top Likes: 0 
#321926 - 08/20/14 10:11 PM Re: Tick disease update [Re: PaddyD]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
smile
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#322401 - 09/01/14 01:04 PM Re: Tick disease update [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Powassan virus in ticks in Hudson Valley, NY
http://www.parasitesandvectors.com/content/6/1/185
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
#322402 - 09/01/14 01:22 PM Re: Tick disease update [Re: MaxaLisa]
MaxaLisa Offline

Global Moderator

Registered: 01/26/10
Posts: 19428
Loc: Northern CA
Likes: 254
Egads, bartonella maybe from spiders, lice, bees, bull ant,
http://www.parasitesandvectors.com/content/6/1/98
_________________________
MaxaL (aka LisaT)

Jazmine, mini-mix, 10/18/2011
Max-n-Indy
Max, 5/2001-2/2012, RIP my partner, my Regal Boy
Indy, 5/1997-10/2010, RIP my friend, my teacher

Health Index
K9 TBD info and Tick List Links
http://www.rabieschallengefund.org/

Top Likes: 0 
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